Joseph DeSimone Image Map
Nov 112016

Prof. Shaomin Tian  &  Prof. Chris Luft

UNC’s School of Medicine has highlighted a new paper published in PLoS Neglected Tropical Diseases focused on a novel nanoparticle vaccine targeting dengue virus. Using the PRINT nano-molding technology invented in the DeSimone lab, the new vaccine demonstrates increased antibody responses against one of the four dengue serotypes. Additional research will focus on adapting the platform to also target the other three dengue serotypes.

DeSimone group members, Prof. Chris Luft and Prof. Shaomin Tian, played key roles in this work and are authors on PLoS NTD paper. Tian is a co-lead author with Dr. Stefan Metz of Prof. Aravinda de Silva’s lab, and Prof. Luft is co-corresponding author with Prof. de Silva. The paper has been featured numerous times, including in ScienceDailyCosmos, Medical XpressInnovation Toronto, MicrobiologyBytes, AZoNano, Outbreak News Today, and Futurism.

UNC SOM article “Can nanotechnology help develop a workable dengue virus vaccine?” by Caroline Curran

“Nanoparticle vaccinates mice against dengue fever” published in ScienceDaily

“Scientists Developed a Vaccine That Could Protect 350 Million Lives” published in Futurism

Read the PLoS NTD paper: “Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

 November 11, 2016