Joseph DeSimone Image Map
Apr 172015
 
Developed in the DeSimone lab in 2004, the PRINT® technology is central to both our life science and materials science research. A powerful nano-molding technique, PRINT enables the fabrication of particles with precise control over the shape, size, composition, and surface functionality. Figures 2 and 3 below illustrate the breadth of shapes, sizes, and compositions possible for nanoparticle fabrication using PRINT.

The PRINT Process

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Figure 1. A unique liquid fluoropolymer (green) is poured on the surface of the master template (gray) and photochemically cross linked. The template is then peeled away to generate a precise mold with micro- or nanoscale cavities. A pre-particle solution (red) is distributed evenly in the mold, which then solidifies. Particles are removed from the mold by bringing the mold in contact with a harvesting film (yellow). Dissolution of the film yields free-flowing particles in solution, enabling them to be easily handled, chemically modified, and analyzed.

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Figure 2. Micron-sized PRINT particles.
print_figure3Figure 3. Nano-sized PRINT particles.
 April 17, 2015