Joseph DeSimone Image Map
Aug 122016
 

Kapadia_2016Congratulations to Dr. Chintan Kapadia, who has been selected to receive an award for scientific engagement by the Gordon Research Conferences (GRC)! The award, for ‘most engaged person’ at the Drug Carriers in Medicine & Biology GRC in Waterville Valley, NH, recognizes Dr. Kapadia’s enthusiasm, engagement, and ability to generate highly stimulating discussions during the conference. For his efforts, he will receive a cash prize and copy of “Handbook of Immunological Properties of Engineered Nanomaterials” signed by renowned scientist, Dr. David Grainger.

Currently a postdoctoral researcher, Dr. Kapadia has been a member of the DeSimone lab since 2012. He recently graduated with his Ph.D. in Pharmaceutical Sciences after defending his dissertation, which focused on engineering PRINT nanoparticle-based subunit vaccines to induce an antitumor immune response.

 August 12, 2016
Jul 122016
 

tiniest doctors image cf desimone groupA new article published by the National Science & Technology Medals Foundation highlights the DeSimone lab’s research in the area of nanomedicine. Dr. DeSimone, a recent recipient of the National Medal of Technology & Innovation, is quoted in the article, which focuses broadly on how nanotechnology is revolutionizing the field of medicine.

Here in the lab, researchers are focused on using the Particle Replication in Nonwetting Templates (PRINT) technology to engineer nanoparticles for applications in oncology and vaccine design. Invented in the DeSimone lab, PRINT enables the fabrication of uniform nanoparticles with precise and independent control over attributes such as shape, size, composition, modulus, and surface chemistry.

Read the article by Allie Bidwell

 July 12, 2016
Jul 072016
 

stent_photo_2016The U.S. Food & Drug Administration (FDA) has approved the Absorb Bioresorbable Vascular System (BVS) for the treatment of coronary artery disease. It is the first and only fully dissolving, drug-eluting cardiac stent. In 2002, Dr. DeSimone made key contributions in developing materials for the stent, leading him to co-found Bioabsorbable Vascular Solutions (also known as BioStent) in partnership with Duke cardiologist, Richard Stack. Guidant acquired Bioabsorbable Vascular Solutions in 2003, and when Boston Scientific acquired Guidant, the stent franchise was sold to Abbott, which now markets the technology.

The dissolvable stent supports a patient’s clogged artery with the same strength as a traditional metal stent, but then uniquely dissolves completely over time after blood flow has been restored to the heart and the vessel is able to stay open on its own. This promotes healing by enabling a vessel to regain its natural flexibility without being inhibited by a permanent metal device.

The new device advanced rapidly through clinical trials worldwide, is now available in over 100 countries, and has been used in over 150,000 patients.

Read Abbott’s press release

 July 7, 2016
May 232016
 

NMTI screen grab 1 zoomOn Thursday, May 19th, Prof. DeSimone was presented with the National Medal of Technology and Innovation by President Barack Obama at a White House ceremony. The Medal recognizes DeSimone’s “pioneering innovations in material science that led to the development of technologies in diverse fields from manufacturing to medicine; and for innovative and inclusive leadership in higher education and entrepreneurship”. Created by statute in 1980, The National Medal of Technology and Innovation recognizes those who have made lasting contributions to America’s competitiveness and quality of life and helped strengthen the Nation’s technological workforce. Congratulations, Prof. DeSimone!

Read UNC’s article by Brandon Bieltz

Watch UNC’s video on the White House event

Read NC State’s article

Read the White House press release

Watch the full White House ceremony here:

 

 May 23, 2016
May 132016
 

Tojan_GradSpeaker__1DeSimone lab member, Tojan Rahhal, was chosen by UNC’s Eshelman School of Pharmacy to be the student speaker at the School’s graduation ceremony on May 7th. Addressing fellow Pharmacy PhD recipients, PharmDs, and Master of Science students regarding future career paths, Rahhal emphasized the importance of harnessing passions cultivated at UNC as professional students.

In addition to being elected to three UNC honor societies, Rahhal graduated last week with the honor of being chosen as a Graduate School Leadership Development Scholar for her efforts to found and launch a new initiative in the School of Pharmacy called the Cross-Cultural Leadership Development (CCLD) workshop program. CCLD workshops are on focused advancing student leadership skills as they relate to diversity and understanding cultural differences.

Rahhal was also recently featured as part of UNC’s “Women in Science Wednesday” series in UNC’s Endeavors magazine.

Read the April 2016 Endeavors “Women in Science Wednesday” feature on Rahhal

 May 13, 2016