Congratulations to Cassie Caudill, who successfully defended her dissertation on September 28th! Caudill’s research focused on the development of microneedles, arrays of micron-scale needles that pierce the skin and facilitate the delivery of therapeutics through the skin in a minimally-invasive manner. Her dissertation, “Engineering Microneedles for the Transdermal Delivery of Therapeutics,” focused on using two technologies, PRINT and CLIP, to manufacture polymeric microneedles for drug delivery applications. Her work addresses the need for scalable and controlled fabrication of microneedles devices, which can be used to transdermally deliver a range of potential therapeutics, including small molecules, proteins, and nanoparticles.
Congratulations to Adam Quintanilla, who successfully defended his dissertation on September 25th! His dissertation, “Fundamentals of Particulate-Filled Polymer Composite via Continuous Liquid Interface Production,” focused on the effect of heterogenous phases (solid or liquid) within photocurable resin for the CLIP process. Quintanilla’s work used mechanical, thermal, and kinetic techniques to investigate the effect of fillers on liquid deadzone formation and thickness, the location and distribution of filler within 3D printed objects, and the potential for formulating printable rubber-toughened thermosets. This effort provides the groundwork for enabling polymer composites fabrication directly using CLIP.
Quintanilla’s career aspirations include pursuing a process engineering or project leadership/management role within a chemical engineering industry.
Congratulations to Cameron Bloomquist, who successfully defended his dissertation on September 28th! Bloomquist’s dissertation, “Continuous Liquid Interface Production of Medical Devices for Drug Delivery and Cancer Therapy,” explored how small molecule drug release can be controlled through design and formulation parameters such as device geometry, crosslink density, and polymer network composition. This work also characterized the clinical suitability of CLIP devices, including analysis of drug stability to the CLIP process and biocompatibility of the resulting part. These lessons were applied to the development of a drug-eluting implantable device for reducing the incidence of tumor recurrence following surgical resection.
In his career, Bloomquist is seeking to apply his research and leadership experience towards industry roles focused on biomaterials development and drug delivery.
Congratulations to Professor DeSimone, who has been named the winner of the 22nd Heinz Award in the Technology, Economy, and Employment category! The honor recognizes DeSimone’s achievements and leadership in multiple fields, including green chemistry, nanomedicine, and 3D printing. “By pursuing research paths at the interface of diverse disciplines, my students, coworkers and I have developed new technologies that, over time, have influenced areas including manufacturing and medicine,” DeSimone said. “This award is a testament not just to our discoveries, but to our approach to research—bringing together people with diverse backgrounds and expertise to solve difficult scientific challenges, ultimately to create a positive impact in the world.”
On April 18th Prof. DeSimone delivered The Fred Kavli Distinguished Lectureship in Materials Science at the 2017 Spring Meeting of the Materials Research Society (MRS). After the talk, titled “Future Fabricated with Light,” DeSimone sat down for an interview with MRS. Both the lecture and interview focused on developments using the rapid 3D printing technology, CLIP.