Joseph DeSimone Image Map
Jun 182013
 

desimone_lores_2013_cropJoseph M. DeSimone is the Chancellor’s Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill, and the William R. Kenan Jr. Professor of Chemical Engineering at NC State University and of Chemistry at UNC. He is a member of all three U. S. National Academies– the National Academy of Medicine (2014), the National Academy of Sciences (2012), and the National Academy of Engineering (2005). He is also a member of the American Academy of Arts and Sciences (2005). DeSimone has published over 350 scientific articles, holds roughly 200 patents, and has received over 50 major awards and recognitions. More about Prof. DeSimone…

Click here for Prof. DeSimone’s Curriculum Vitae

 June 18, 2013
May 202013
 
Graduate Students
Cameron_BloomquistCameron Bloomquist
cbloomq@email.unc.edu
234 Caudill
(919) 962-3396
cassie_caudill_2014Cassie Caudill
caudillc@email.unc.edu
233 Caudill
(919) 962-3396
Jason_Coffman_2014Jason Coffman
jecoffma@ncsu.edu
2119 Marsico
placeholder_unc_logo1Rima Janusziewicz
januszrx@email.unc.edu
255 Caudill
(919) 962-3396
Kevin_Olsen_2014Kevin Olson
kevino@live.unc.edu
233 Caudill
(919) 962-3396
ncsu_logoAdam Quintanilla
alquinta@ncsu.edu
234 Caudill
(919) 962-3396
erin_wilson_2014Erin Wilson
wilson85@email.unc.edu
2119 Marsico
Post-doctoral Fellows
ERAS photoJames Byrne
james_byrne@med.unc.edu
2119 Marsico
Ali Nebipasagilali
alinebipasagil@unc.edu
240 Caudill
(919) 962-3396
Ying_Wang_2013Ying Wang
ywangjlu@email.unc.edu
2119 Marsico

 

 May 20, 2013
May 182013
 
crista-fCrista Farrell
Project Manager
farrellc@email.unc.edu
(609) 790-6360
chris_luftChris Luft
Research Associate Professor
Division of Molecular Pharmaceutics
UNC Eshelman School of Pharmacy
jluft@email.unc.edu
2119 Marsico
(919) 962-6303
Sue_Mecham_2014Sue Mecham
Research Associate
sjmecham@unc.edu
237 Caudill
(919) 962-8448
jill_perryJillian Perry
Research Associate
perryjl@email.unc.edu
2119 Marsico
bob_pinschmidt_2015Bob Pinschmidt
Research Associate
rkp@unc.edu
251 Caudill
(919) 962-3396
shaomin-tianShaomin Tian
Research Assistant Professor
Department of Microbiology & Immunology
UNC School of Medicine
smtian@email.unc.edu
2119 Marsico
(919) 962-6839
yi_xianwenXianwen Yi
Research Associate
xianwen_yi@med.unc.edu
2119 Marsico

 

 May 18, 2013
May 162013
 
bill_holtonWilliam C. Holton
Research Professor, NC State Univ.
Dept. of Electrical & Computer Engineering
holton@ncsu.edu
Box 7911 / NCSU Campus

 

 May 16, 2013
Feb 172010
 

desimone_lores_2013_cropProfessor DeSimone is the Chancellor’s Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill, and the William R. Kenan, Jr. Professor of Chemical Engineering at NC State University and of Chemistry at UNC. He is also an adjunct member at Memorial Sloan-Kettering Cancer Center. DeSimone has published over 350 scientific articles and has roughly 200 issued patents in his name with over 200 patents pending.

DeSimone is one of only a few individuals who has been elected to all three branches of the U. S. National Academies: the National Academy of Medicine (2014), the National Academy of Sciences (2012), and the National Academy of Engineering (2005). He is also a member of the American Academy of Arts and Sciences (2005).

In May 2016 DeSimone was recognized by President Barack Obama with the U.S. National Medal of Technology and Innovation, the highest honor in the U.S. for achievement  and leadership in advancing technological progress. DeSimone has received over 50 other major awards and recognitions including the 2015 Kabiller Prize in Nanoscience and Nanomedicine; the 2015 Dickson Prize from Carnegie Mellon University; the 2014 Industrial Research Institute Medal; the 2014 Kathryn C. Hach Award for Entrepreneurial Success from the ACS; 2013 Fellow of the National Academy of Inventors; the 2012 Walston Chubb Award for Innovation presented by Sigma Xi; the 2010 AAAS Mentor Award in recognition of his efforts to advance diversity in the chemistry PhD workforce; the 2009 NIH Director’s Pioneer Award; the 2009 North Carolina Award, the highest honor the State of North Carolina can bestow to recognize notable achievements of North Carolinians in the fields of Literature, Science, the Fine Arts and Public Service; the 2008 Lemelson-MIT Prize for Invention and Innovation; the 2008 Tar Heel of the Year by the Raleigh News & Observer; the 2007 Collaboration Success Award from the Council for Chemical Research; the 2005 ACS Award for Creative Invention; the 2002 John Scott Award presented by the City Trusts, Philadelphia, given to “the most deserving” men and women whose inventions have contributed in some outstanding way to the “comfort, welfare and happiness” of mankind; the 2002 Engineering Excellence Award by DuPont; the 2002 Wallace H. Carothers Award from the Delaware Section of the ACS; and the 2000 Oliver Max Gardner Award from the University of North Carolina, given to that person, who in the opinion of the Board of Governors’ Committee, “. . . during the current scholastic year, has made the greatest contribution to the welfare of the human race”.

DeSimone’s notable inventions include an environmentally friendly manufacturing process that relies on supercritical carbon dioxide instead of water and bio-persistent surfactants (detergents) for the creation of fluoropolymers or high-performance plastics, such as Teflon®. In 2002 DeSimone, along with Dr. Richard Stack (Duke University) and Dr. Robert Langer (MIT), co-founded Bioabsorbable Vascular Solutions (BVS) to commercialize a fully bioabsorbable, drug-eluting stent. Among other inventions, DeSimone has also developed novel, nonflammable electrolytes for lithium-ion batteries that are being commercialized.

DeSimone’s research group is heavily focused on harnessing the fabrication technologies from the semiconductor industry to design high-performance, cost-effective vaccines and medicines. DeSimone and his team developed a roll-to-roll particle fabrication technology called PRINT (Particle Replication in Non-wetting Templates) in 2004. The group is now exploiting the advantages of PRINT to generate “calibration quality” nano-tools to define the geometric (size, shape), surface (zeta potential, stealthing ligands), and deformability limitations associated with the delivery of drugs and vaccines using different dosage forms. DeSimone’s laboratory and the PRINT technology became a foundation for the Carolina Center for Cancer Nanotechnology Excellence funded by the National Cancer Institute.

In 2004 DeSimone launched Liquidia Technologies, which employs roughly 50 people in RTP and has raised over $60 million in venture financing, including the first ever equity investment by the Bill and Melinda Gates Foundation in a for-profit biotech company. Liquidia has converted PRINT into a GMP compliant process and is building on promising clinical trial results for its products.

Currently, DeSimone is on sabbatical leave from the university and has assumed the CEO role at Carbon, Inc. in Silicon Valley after co-founding the company based on a recent breakthrough in 3D printing called Continuous Liquid Interface Production (CLIP). Students in the DeSimone research group are also focused on using CLIP to explore fundamental advances in applying 3D printing for the creation of new medical devices.

DeSimone received his BS in Chemistry in 1986 from Ursinus College in Collegeville, PA and his Ph.D. in Chemistry in 1990 from Virginia Tech.

Click here for Prof. DeSimone’s Curriculum Vitae

 

 February 17, 2010